A new study published in Orphanet Journal of Rare Diseases shows that patients with rare conditions have reduced  health-related quality of life (HRQL) compared to patients with more common conditions. The analysis by Kathleen Bogart and Veronica Irvin of Oregon State University involved 1218 patients who completed a survey who represented 232 rare diseases. The researchers found that for all domains of the HRGL (anxiety, depression, fatique, pain, physical function, social activities), scores were lower in the rare disease patients compared to those with common ailments. The lowest scores were found in women and in patients with lower incomes.